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Records: Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction

Studies show the peptide increases dendritic spine density by 40-60% in treated brain regions, with formation of new functional synaptic connections confirmed by electrophysiological recordings demonstrating enhanced synaptic transmission and long-term potentiation

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Its long action profile supports a single weekly subcutaneous dose , holding steady exposure between injections and making once-weekly administration practical [3]